PurposeTo guide the drug selection for treatment of moderate to severe ulcerative colitis (UC) by evaluating the efficacy and safety of various drugs. MethodsThis systematic review searched the Embase. PubMed. The Cochrane Library. https://www.roneverhart.com/ASUS-VivoBook-X515-15-6-FHD-Laptop-Intel-Core-i5-1135G7-2-4-GHz-Intel-Iris-Xe-Graphics-16GB-DDR4-RAM-1TB-SSD-Windows-/